Sergei S. Pilyugin
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E-mail: pilyugin@ufl.edu

358 Little Hall
Dept. of Mathematics
University of Florida
Gainesville, FL 32611-8105

Office: 352-392-0281 Ext. 296
Fax: 352-392-8357

 Sergei

Sergei S. Pilyugin

2012/13 Allan R. and Margaret G. Crow
Professor of Mathematics

You still think it is not a game? The game does not think so -:)

 


My research spans several areas between mathematics and biology. Trained in differential equations and functional analysis, I gradually acquired a taste for biological applications. My relationship with the biological sciences can be roughly classified as symbiotic (peaceful coexistence). I like to play with other peoples' data and make excuses for studying some far-fetched theoretical abstractions called "mathematical models". In recent years, I partly succumbed to the popular in silico modeling trend and started playing with computer simulations.

There is a number of ongoing projects that I am working/collaborating/having fun with

  1. Adaptive dynamics of microbial metabolism
  2. Dynamics of controlled bioreactors
  3. Evolution of drug resistance in bacteria
  4. Generation and maintenance of immunological memory
  5. Within and between host parasite dynamics with mutations
  6. Theoretical ecology of microbes and parasites
  7. Dynamics of neural networks

Recent publications:

  • C. J. Browne and S. S. Pilyugin (2011), Periodic multidrug therapy in a within-host virus model, Bull. Math. Biol., PMID: 21822766. PDF

  • S. F. Ellermeyer and S. S. Pilyugin (2011), A size-structured model of bacterial growth and reproduction, J. Biol. Dyn., DOI:10.1080/17513758.2010.535127. PDF

  • P. De Leenheer, J. Dockery, T. Gedeon, and S. S. Pilyugin (2010), The chemostat with lateral gene transfer, J. Biol. Dyn. 4 (6), pp. 607-620. PDF

  • P. De Leenheer, J. Dockery, T. Gedeon, and S. S. Pilyugin (2010), Senescence and antibiotic resistance in an age-structured population model, J. Math. Biol. 61 (4), pp. 475-499. PDF

  • J. T. Noel, S. S. Pilyugin, and A. Narang (2009), The diffusive influx and carrier efflux have a strong effect on the bistability of the lac operon in Escherichia coli, J. Theor. Biol. 256 (1), pp. 14-28. PDF

  • A. Handel, A. Yates, S. S. Pilyugin, and R. Antia (2009), Sharing the burden: Antigen transport and firebreaks in immune responses, J. Royal Soc. -Interface 6 (34), pp. 447-454. PDF

  • P. De Leenheer and S. S. Pilyugin (2008), Multi-strain virus dynamics with mutations: A global analysis, Math. Med. and Biol. 25 (4), pp. 285-322. PDF

  • A. Narang and S. S. Pilyugin (2008), Bistability of the lac operon during growth of Escherichia coli on lactose and lactose + glucose, Bull. Math. Biol. 70 (4), pp. 1032-1064. PDF

  • P. De Leenheer, W. S. Keeran, and S. S. Pilyugin (2008), Feedback-mediated coexistence and oscillations in the chemostat, DCDS - B 9 (2), pp. 321-351. PDF

    • Research supported by:

  • Modeling microbial heterogeneity under antibiotic treatment (NSF DMS -0818050)
    • Last modified 07 May 2012