Title: Iteratively Regularized Gauss Newton Algorithm With Adaptive Parameter Space Update For Reconstruction In Diffuse Optical Tomography -T. Khan (Clemson University) and A. Smirnova (Georgia State University) Abstract: Diffuse optical tomography (DOT), as a potential medical imaging modality, has been investigated for more than a decade. The idea of DOT is the reconstruction of the spatial distribution of optical properties within tissue by use of measurements of near-infrared diffusive light along the tissue boundary. In this talk, an iteratively regularized Gauss-Newton algorithm with adaptive parameter space update for the inverse problem associated with the reconstruction of the spatial distribution of optical properties in DOT, will be discussed. We will present our reconstruction results based on this algorithm and discuss some of the open questions and challenges.